Journal of Clinical and Scientific Research

ORIGINAL ARTICLE
Year
: 2021  |  Volume : 10  |  Issue : 2  |  Page : 97--102

Clinical utility of 18fluorodeoxyglucose positron emission tomography-computed tomography in rheumatology


Sirisha Kommireddy1, Ranadheer Mantri1, Sabella Aparna Reddy2, D Ravisankar2, Tekchand Kalawat3 
1 Department of Rheumatology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
2 Department of Community Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India
3 Department of Nuclear Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India

Correspondence Address:
Ranadheer Mantri
Associate Professor, Department of Nuclear Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507, Andhra Pradesh
India

Background: Several studies with 18fluorodeoxyglucose positron emission tomography with computed tomography (18FDG PET-CT) have indicated that 18fluorodeoxyglucose uptake in affected tissues reflects the disease activity. In addition, the usage of PET-CT for early detection, extent and monitoring of the treatment response has been reported. Methods: In this retrospective study, all 18FDG PET-CTs requested by rheumatologists were reviewed retrospectively. The clinical findings and scan findings were noted. Considering the final diagnosis made by the clinician as “gold standard”, he sensitivity, specificity and positive were calculated. Results: Out of 48, 18FDG PET-CT requests, two were excluded (39 females, mean age – 39.22 ± 15.349). The indications included establishing diagnosis (n = 31 [67.4%]) and disease activity/extent (n = 15 [32.6%]). It contributed to the diagnosis in 9 (31%), when 18F FDG PETCT is used for establishing the diagnosis. It identified abnormalities in 14/15 when used for disease activity and active disease was identified in 10. Seventeen patients had a final diagnosis of fibromyalgia. Overall, 18FDG PET-CT had 100 sensitivity and NPV. The diagnostic accuracy was 56.52%. Conclusions: The 18FDG PET-CT has high diagnostic sensitivity and poor specificity in rheumatology practice with respect to establishing the diagnosis as well as to detect the extent and activity of disease.


How to cite this article:
Kommireddy S, Mantri R, Reddy SA, Ravisankar D, Kalawat T. Clinical utility of 18fluorodeoxyglucose positron emission tomography-computed tomography in rheumatology.J Clin Sci Res 2021;10:97-102


How to cite this URL:
Kommireddy S, Mantri R, Reddy SA, Ravisankar D, Kalawat T. Clinical utility of 18fluorodeoxyglucose positron emission tomography-computed tomography in rheumatology. J Clin Sci Res [serial online] 2021 [cited 2021 Sep 23 ];10:97-102
Available from: https://www.jcsr.co.in/article.asp?issn=2277-5706;year=2021;volume=10;issue=2;spage=97;epage=102;aulast=Kommireddy;type=0