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Year : 2020  |  Volume : 9  |  Issue : 2  |  Page : 101-104

A study of microbiome and its antimicrobial susceptibility patterns among central line-associated bloodstream infections

Department of Microbiology, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India

Correspondence Address:
Jayaprada Rangineni
Assistant Professor, Department of Microbiology, Sri Venkateswara Institute of Medical Sciences, Tirupathi, Andhra Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCSR.JCSR_34_19

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Introduction: Central line-associated bloodstream infections (CLABSIs) are the most frequent cause of health-care-associated infections and significantly increase cost and hospital length of stay. Methods: We retrospectively studied hospitalised patients having a central line access during the period 2016-2018, to study patients with CLABSI at our tertiary care hospital. Results: Average CLABSI rate was 16.7 per 1000 central line days for 3 years. Most of the infections were caused by Staphylococcus aureus (18.9%), followed by non-fermentative Gram-negative bacilli (NFGNB) (16%), Klebsiella spp. (15.1%), Acinetobacter spp. (14.2%) and coagulase-negative Staphylococcus ( CoNS) (13.2%). A higher proportion of CLABSI was observed with femoral lines (59.7%), followed by jugular lines (35.8%) and subclavian lines (9.4%). This study showed multidrug-resistant pathogens as a causative agent of CLABSI. Conclusion: CLABSI is a common entity, especially in intensive care unit settings. S. aureus, NFGNB, Klebsiella spp., Acinetobacter spp. and CoNS were the common pathogens isolated in our study. Strict implementation of CLABSI bundle care plays an important role to minimise the CLABSI rate.

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