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  Indian J Med Microbiol
 

Figure 4: Chest radiograph (postero-anterior view) showing an ill-defined opacity (arrow) in the left hilar region and Ill-defined areas of consolidation in the right upper- and mid-zones (a). Axial NCCT of the Chest (mediastinal window) (b), CECT of the chest (mediastinal window) (c) (lung window) (d) showing a lobulated mass lesion in the superior segment of the left lower lobe (arrow) which is isodense on NCCT (b) and is enhancing homogeneously on CECT (c). Maximum intensity projection image showing physiological FDG uptake in the brain, heart, liver, kidney and bladder and abnormal FDG uptake in thorax and mediastinum (e). Axial CT (f) and fused PET-CT (g) showing intensely increased FDG concentration in an irregular soft-tissue density lesion in the left hilar region measuring 5.2 cm × 4.5 cm with SUVmax 13.7. Axial CT (h) and fused PET-CT (i) showing right lower paratracheal lymph nodes measuring 2.1 cm × 1.2 cm with SUVmax 8.2. Photomicrograph of CT-guided lung biopsy shows tumour cells with hyperchromatic nuclei, inconspicuous nucleoli, nuclear moulding and scanty cytoplasm arranged diffusely in foci with necrosis suggestive of small cell carcinoma (j) (Hematoxylin and eosin, × 200). Photomicrograph showing positivity for CD56 (k), synaptophysin (l), chromogranin (m) in tumour cells of Tru-cut lung biopsy suggestive of small cell carcinoma. NCCT = Non-contrast computed tomography; CECT = Contrast-enhanced computed tomography; CT = Computed tomography; PET-CT = Positron emission tomography-computed tomography; SUVmax = Maximum standardised uptake value; FDG = Fluorodeoxyglucose; CD = cluster of differentiation

Figure 4: Chest radiograph (postero-anterior view) showing an ill-defined opacity (arrow) in the left hilar region and Ill-defined areas of consolidation in the right upper- and mid-zones (a). Axial NCCT  of the Chest (mediastinal window) (b), CECT of the chest (mediastinal window) (c)  (lung window) (d) showing a lobulated mass lesion in the superior segment of the left lower lobe (arrow) which is isodense on NCCT (b) and is enhancing homogeneously on CECT (c). Maximum intensity projection image showing physiological FDG uptake in the brain, heart, liver, kidney and bladder and abnormal FDG uptake in thorax and mediastinum (e). Axial CT (f) and fused PET-CT (g) showing intensely increased FDG concentration in an irregular soft-tissue density lesion in the left hilar region measuring 5.2 cm × 4.5 cm with SUV<sub>max</sub> 13.7. Axial CT (h) and fused PET-CT (i) showing right lower paratracheal lymph nodes measuring 2.1 cm × 1.2 cm with SUV<sub>max</sub> 8.2. Photomicrograph of CT-guided lung biopsy shows tumour cells with hyperchromatic nuclei, inconspicuous nucleoli, nuclear moulding and scanty cytoplasm arranged diffusely in foci with necrosis suggestive of small cell carcinoma (j) (Hematoxylin and eosin, × 200). Photomicrograph showing positivity for CD56 (k), synaptophysin (l), chromogranin (m) in tumour cells of Tru-cut lung biopsy suggestive of small cell carcinoma. NCCT = Non-contrast computed tomography; CECT = Contrast-enhanced computed tomography;  CT = Computed tomography; PET-CT = Positron emission tomography-computed tomography; SUV<sub>max</sub> = Maximum standardised uptake value; FDG = Fluorodeoxyglucose; CD  = cluster of differentiation