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  Indian J Med Microbiol
 

Figure 2: Chest radiograph (postero-anterior view) showing a well-defined opacity (arrow) in the left upper- and mid-zone. Hilar vessels are clearly seen with in the opacity, and the mass is showing acute angle with aortic silhouette-suggestive of a lung pathology (a). Axial NCCT of the chest (mediastinal window) (b), CECT of the chest (mediastinal window) (c), (lung window) (d) showing a mass lesion in the apico-posterior segment of the left upper lobe (red arrow) with peripheral enhancing solid component and central non-enhancing necrotic area. Maximum intensity projection image showing physiological FDG uptake in the brain, liver, kidney and bladder and abnormal FDG uptake in neck, thorax region (e). Axial CT (f) another patient and fused PET-CT (g) image showing soft-tissue density lesion in the anterior segment of the left lung upper lobe abutting the mediastinum measuring 5.1 cm × 2.4 cm with SUVmax 6.4 and right massive pleural effusion. Sagittal CT (h) and fused PET-CT (i) showing increased FDG uptake in multiple mixed lytic and sclerotic lesions in dorsal, lumbar and sacral vertebrae. Photomicrograph of CT-guided lung biopsy specimen showing cuboidal cells with mild nuclear pleomorphism, eosinophilic cytoplasm arranged in the form of glands in a suggestive of adenocarcinoma (Haematoxylin and eosin, × 200) (j). Photomicrograph (x 200) of immunohistochemistry showing diffuse cytoplasmic positivity of cytokeratin 7(k), thyroid transcription factor-1 (TTF-1) (l), Napsin-A (m) in the lesional cells of Tru-cut lung biopsy suggestive of adenocarcinoma. NCCT = Non-contrast computed tomography; CECT = Contrast-enhanced computed tomography; CT = Computed tomography; PET-CT = Positron emission tomography-computed tomography; SUVmax = Maximum standardised uptake value; FDG = Fluorodeoxyglucose

Figure 2:  Chest radiograph (postero-anterior view) showing a well-defined opacity (arrow) in the left upper- and mid-zone. Hilar vessels are clearly seen with in the opacity, and the mass is showing acute angle with aortic silhouette-suggestive of a lung pathology (a). Axial NCCT of the chest  (mediastinal window) (b), CECT of the chest (mediastinal window) (c), (lung window) (d) showing a mass lesion in the apico-posterior segment of the left upper lobe (red arrow) with peripheral enhancing solid component and central non-enhancing necrotic area. Maximum intensity projection image showing physiological FDG uptake in the brain, liver, kidney and bladder and abnormal FDG uptake in neck, thorax region (e). Axial CT (f) another patient and fused PET-CT (g) image showing soft-tissue density lesion in the anterior segment of the left lung upper lobe abutting the mediastinum measuring 5.1 cm × 2.4 cm with  SUV<sub>max</sub> 6.4 and right massive pleural effusion. Sagittal CT (h) and fused PET-CT (i)  showing increased FDG uptake in multiple mixed lytic and sclerotic lesions in dorsal, lumbar and sacral vertebrae. Photomicrograph of CT-guided lung biopsy  specimen showing cuboidal cells with mild nuclear pleomorphism, eosinophilic cytoplasm arranged in the form of glands in a suggestive of adenocarcinoma (Haematoxylin and eosin, × 200) (j). Photomicrograph (x 200) of immunohistochemistry showing diffuse cytoplasmic positivity of cytokeratin 7(k), thyroid transcription factor-1 (TTF-1) (l), Napsin-A (m) in the lesional cells of Tru-cut lung biopsy suggestive of adenocarcinoma. NCCT = Non-contrast  computed tomography; CECT = Contrast-enhanced computed tomography; CT = Computed tomography; PET-CT = Positron emission tomography-computed tomography; SUV<sub>max</sub> = Maximum standardised uptake value; FDG = Fluorodeoxyglucose