• Users Online: 100
  • Print this page
  • Email this page
Year : 2019  |  Volume : 8  |  Issue : 3  |  Page : 159-161

Methaemoglobinaemia due to nitrobenzene poisoning

Department of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati, Andhra Pradesh, India

Correspondence Address:
D T Katyarmal
Associate Professor, Department of Medicine, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507, Andhra Pradesh
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCSR.JCSR_63_19

Rights and Permissions

An acute poisoning with nitrobenzene presenting as methaemoglobinaemia is an uncommon medical emergency. Here, we report the case of a 33-year-old male presenting with an alleged history of consumption of an unknown substance 24 h ago. On admission, he was unconscious (Glasgow Coma Scale score 3) and gasping. General physical examination revealed cyanosis of the fingers, lips and tongue, pulse: 128/min, blood pressure: 98/70 mmHg and arterial oxygen saturation by pulse oximeter (SpO2): 70%. Pupils on both sides were dilated and sluggishly reacting to light. Respiratory system examination revealed bilateral basal crepitations. Rest of the physical examination was normal. Tracheal intubation was done, and he was initiated on mechanical ventilator support. Arterial blood gas analysis showed pH: 7.28; arterial carbon dioxide tension (PaCO2): 29.9 mmHg, arterial oxygen tension (PaO2): 45 mmHg, arterial oxygen saturation (SaO2): 83.8% and bicarbonate: 13.4 mEq/L. In spite of mechanical ventilator support, he continued to have hypoxia and cyanosis. Saturation gap was calculated to be 13%. In view of which methaemoglobinaemia was considered and blood sample has been sent for methaemoglobin levels and started him on injectable methylene blue and ascorbic acid. After a week, hypoxia and cyanosis improved and he was discharged in a haemodynamically stable condition.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded37    
    Comments [Add]    

Recommend this journal