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CORRESPONDENCE
Year : 2019  |  Volume : 8  |  Issue : 2  |  Page : 113

Screening for thyroid disorders in medical undergraduate students


Department of Paediatrics, Al-Kindy College of Medicine, University of Baghdad, Baghdad, Iraq

Date of Web Publication11-Nov-2019

Correspondence Address:
Mahmood Dhahir Al-Mendalawi
P.O. Box 55302, Baghdad Post Office, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCSR.JCSR_43_19

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How to cite this article:
Al-Mendalawi MD. Screening for thyroid disorders in medical undergraduate students. J Clin Sci Res 2019;8:113

How to cite this URL:
Al-Mendalawi MD. Screening for thyroid disorders in medical undergraduate students. J Clin Sci Res [serial online] 2019 [cited 2019 Dec 9];8:113. Available from: http://www.jcsr.co.in/text.asp?2019/8/2/113/270748



I read the study by Nikhita et al.[1] published in April–June 2018 issue of the Journal of Clinical and Scientific Research. Using thyroid function tests (TFTs), the authors screened for thyroid disorders medical undergraduate students of 17–19 years of age group studying in Sri Venkateswara Institute of Medical Sciences, Sri Padmavathi Medical College for Women, Tirupati, India.[1] They found among the studied cohort, a single subject with subclinical hypothyroidism. The thyroid-stimulating hormone level of this subject was 8.1 mIU/L that was considered to be mildly elevated from the normal range and the thyroxine level was 89 ng/mL that was within the normal reference range.[1] I assume that such low prevalence of thyroid dysfunctions ought to be cautiously taken owing to the presence of the following methodological limitation. In the methodology, the authors mentioned that they analysed for TFTs on Beckman Coulter Access 2 Autoanalyser (Chaska, Minnesota, USA) by chemiluminescence immunoassay method.[1] It is explicit that interpreting TFTs values in a given population needs reference norms for that population. Actually, certain population-specific TFT reference ranges have been constructed.[2],[3] India has already constructed the mean reference intervals for TFTs for different age groups for both genders separately using strict exclusion criteria to be employed in the clinical setting and researches.[4] Regrettably, Nikhita et al.[1] did not mention which reference intervals of TFTs employed in the study methodology to analyse the data. I assume that employing national reference values could better elucidate the profile of disordered thyroid functions.

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Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Nikhita D, Srinivasa Rao PL, Suresh V. Screening for thyroid disorders in medical undergraduate students. J Clin Sci Res 2018;7:94-6.  Back to cited text no. 1
  [Full text]  
2.
Mirjanic-Azaric B, Avram S, Stojakovic-Jelisavac T, Stojanovic D, Petkovic M, Bogavac-Stanojevic N, et al. Direct estimation of reference intervals for thyroid parameters in the Republic of Srpska. J Med Biochem 2017;36:137-44.  Back to cited text no. 2
    
3.
Park SY, Kim HI, Oh HK, Kim TH, Jang HW, Chung JH, et al. Age- and gender-specific reference intervals of TSH and free T4 in an iodine-replete area: Data from Korean National Health and Nutrition Examination Survey IV (2013-2015). PLoS One 2018;13:e0190738.  Back to cited text no. 3
    
4.
Marwaha RK, Tandon N, Ganie MA, Mehan N, Sastry A, Garg MK, et al. Reference range of thyroid function (FT3, FT4 and TSH) among Indian adults. Clin Biochem 2013;46:341-5.  Back to cited text no. 4
    



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1 Authorsę response
Doppalapudi Nikhita,PV. L. N Srinivasa Rao,Suresh Vaikkakara
Journal of Clinical and Scientific Research. 2019; 8(2): 114
[Pubmed] | [DOI]



 

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