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CASE REPORT
Year : 2017  |  Volume : 6  |  Issue : 3  |  Page : 190-192

Disseminated strongyloidiasis with acute kidney injury


1 Department of Nephrology, Manipal hospitals, Vijayawada, India
2 Department of Biochemistry, Sri Venkateswara Institute of Medical Sciences, Tirupati, India
3 Department of Microbiology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India
4 Department of Nephrology, My cure hospitals, Visakapatnam, India
5 Department of Nephrology, Narayana hospitals, Bangalore, India
6 Department of Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India

Correspondence Address:
V Siva Kumar
Sr.Professor, Department of Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.15380/2277-5706.JCSR.17.05.002

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Strongyloides stercoralis, an intestinal parasitic nematode, infects more than 100 million people worldwide. Strongyloides are unique in their ability to exist as a free-living and autoinfective cycle. Strongyloidiasis infection usually remains asymptomatic, but in immunocompromised hosts hyperinfection and dissemination can occur, which has a high mortality. We report a 30-year-old male patient with membranous nephropathy who was receiving oral corticosteroids and cyclophosphamide who presented with disseminated strongyloidiasis. Larvae of S. stercoralis were isolated from the stool and the sputum specimens. Seven days later despite anti-helminthic therapy and intensive care support the patient died. Early detection and diagnosis of this condition is based on a high index of clinical suspicion, especially in immunocompromised hosts. Screening for Strongyloidiasis infection before the initiation of immunosuppressive therapy can be considered.


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