• Users Online: 52
  • Print this page
  • Email this page
Year : 2014  |  Volume : 3  |  Issue : 4  |  Page : 268-273

Disseminated cryptococcosis in a patient with advanced HIV infection

1 Department of General Medicine, Nizam's Institute of Medical Sciences, Hyderabad, India
2 Department of Microbiology, Nizam's Institute of Medical Sciences, Hyderabad, India
3 Department of Pathology, Nizam's Institute of Medical Sciences, Hyderabad, India

Correspondence Address:
M.V.S Subbalaxmi
Associate Professor, Department of General Medicine, Nizam's Institute Of Medical Sciences, Hyderabad
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.15380/2277-5706.JCSR.14.015

Rights and Permissions

Antiretroviral therapy in human immunodeficiency virus (HIV) patients has prolonged survival and reduced the frequency of opportunistic infections (OI). However, following starting of antiretroviral therapy (ART), some patients experience a paradoxical worsening of clinical condition termed as immune reconstitution inflammatory syndrome (IRIS) an entity, characterized by an excessive inflammatory response to a preexisting antigen or pathogen. Cryptococcus neoformans is one of the important pathogens that can cause an IRIS, in patients with low CD 4 cell counts in HIV patients. It is important to consider the possibility of cryptococcal infection in patients with advanced HIV infection, look for cryptococcal antigen in serum and cerebrospinal fluid along with blood culture. Blood cultures should be kept for further incubation for slow growing organisms by as demonstrated in the present case. We herewith report a case of IRIS due to cryptococcal meningitis in a patient with HIV1 infection with very low CD4 counts.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded16    
    Comments [Add]    

Recommend this journal