• Users Online: 139
  • Print this page
  • Email this page
REVIEW ARTICLE
Year : 2012  |  Volume : 1  |  Issue : 4  |  Page : 178-186

C-reactive protein and coronary heart disease - risk marker or risk factor?


1 Department of Physiotherapy, Manipal College of Allied Health Sciences, Karnataka, India
2 Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India

Correspondence Address:
Sudha Vidyasagar
Professor and Head, Department of Medicine, Kasturba Medical College, Karnataka
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


Rights and PermissionsRights and Permissions

Cardiovascular diseases are gaining a dubious distinction of becoming the leading cause of death. Thus, the search for new risk markers and risk factors of cardiovascular disease continue, in an attempt to predict the risk of cardiovascular events with greater precision. Of all the risk markers available, high sensitivity C-reactive Protein (hsCRP) is considered to be the most robust tool with test characteristics desirable and conducive for clinical use. Pharmacological intervention trials were successful in reducing hsCRP in individuals with elevated levels, following which its status as a therapeutic target has taken a big leap. Numerous pharmacologic and non-pharmacologic interventions are presently being investigated for their efficacy in reducing this inflammatory marker. This review discusses the stability of hsCRP, factors affecting the concentration, independent predictive ability as compared to the traditional risk factors and its role in atherogenesis.


[PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed14    
    Printed1    
    Emailed0    
    PDF Downloaded2    
    Comments [Add]    

Recommend this journal